Asteroid 10653, Witsen, was discovered on September 24, 1960 by C. J. van Houten and Ingrid van Houten-Groeneveld on photographic plates taken by Tom Gehrels at Palomar Mountain Observatory near Pauma Mountain, California. It has a period of 6 years, 348 days.
It was named for Nicolaas Witsen (1641-1717), a Dutch lawyer, politician, scientist, graphic artist, collector, author and cartographer, who was mayor of Amsterdam and governor of the Dutch East India Company, beginning in 1693. In this capacity he initiated research on Asian people, plants and animals.
The astrological meaning of asteroid Witsen seems to be : "at wit's end", having had enough or perhaps as far as your wits can take you.